Accommodating volume-constant age-dependent optical (AVOCADO) model of the crystalline GRIN lens

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Accommodating volume-constant age-dependent optical (AVOCADO) model of the crystalline GRIN lens.

The purpose of this manuscript is to introduce a new age-dependent model of the human lens with two GRIN power distributions (axial and radial) that allow decoupling of its refractive power and axial optical path length. The aspect ratio of the lens core can be held constant under accommodation, as well as the lens volume by varying the asphericity of the lens external surfaces. The spherical a...

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Crystalline lens paradoxes revisited: significance of age-related restructuring of the GRIN.

The accommodating volume-constant age-dependent optical (AVOCADO) model of the crystalline lens is used to explore the age-related changes in ocular power and spherical aberration. The additional parameter m in the GRIN lens model allows decoupling of the axial and radial GRIN profiles, and is used to stabilise the age-related change in ocular power. Data for age-related changes in ocular geome...

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Age-dependent Fourier model of the shape of the isolated ex vivo human crystalline lens

PURPOSE To develop an age-dependent mathematical model of the zero-order shape of the isolated ex vivo human crystalline lens, using one mathematical function, that can be subsequently used to facilitate the development of other models for specific purposes such as optical modeling and analytical and numerical modeling of the lens. METHODS Profiles of whole isolated human lenses (n=30) aged 2...

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OCT-based crystalline lens topography in accommodating eyes.

Custom Spectral Domain Optical Coherence Tomography (SD-OCT) provided with automatic quantification and distortion correction algorithms was used to measure anterior and posterior crystalline lens surface elevation in accommodating eyes and to evaluate relationships between anterior segment surfaces. Nine young eyes were measured at different accommodative demands. Anterior and posterior lens r...

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In vivo measurement of age-related stiffening in the crystalline lens by Brillouin optical microscopy.

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ژورنال

عنوان ژورنال: Biomedical Optics Express

سال: 2016

ISSN: 2156-7085,2156-7085

DOI: 10.1364/boe.7.001985